Amoeboid form main
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| Amoeboid forms (haemozoin)
A solid and angular late trophozoite form of P.malariae. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed). Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B) As trophozoites of P.vivax mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for P.vivax that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites. |