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Thick vs Thin film comparison: Difference between revisions

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IMAGE OF EACH
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File:2_Trophs_MP.jpg|<span style="font-size:80%">Two ring frms of ''P.falciparum''</span>|link={{filepath:2_Trophs_MP.jpg}}
File:3_Trophs_HP.jpg|<span style="font-size:80%">High-power image of the parasites</span>|link={{filepath:3_Trophs_HP.jpg}}
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!colspan="3" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%;">'''COMPARISON OF THICK AND THIN FILMS'''</span></br>
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Revision as of 09:59, 14 February 2025

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 >>>Current page: Thick film vs thin film

Relative merits of thick or thin films in malaria diagnosis

  • Two ring frms of P.falciparum

    Two ring frms of P.falciparum

  • High-power image of the parasites

    High-power image of the parasites


Feature Thick Film Thin Film
Sensitivity for detection Higher: detects low parasitaemia ~5–10 parasites/µL Lower: generally needs ~50 parasites/µL for reliable detection)
Species Identification Poor: RBC morphology lost and species-specific features may be difficult Excellent: Parasite morphology and RBC characteristics are readily observed
Quantification of parasitaemia Difficult: requires estimation so is imprecise Easier: parasites can be counted per number of RBCs
Preparation and staining Longer: requires air drying before careful staining to avoid artefact Faster: films are fixed and stained immediately with clearer morphology


COMPARISON OF THICK AND THIN FILMS
1. Sensitivity for detection
Thick film: Higher - can detect lower levels of parasitaemia ~5–10 parasites/µL
Thin film: Lower - generally requires ~50 parasites/µL for reliable detection
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