Amoeboid form main: Difference between revisions

Revision as of 18:14, 12 December 2024

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Amoeboid forms (haemozoin) A solid and angular late trophozoite form of P.malariae. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed). The late trophozoite of P.vivax becomes more solid, but with an irregular form that is said to resemble an amoeba with extended processes. Other features of the species will also be detected. Species significance A fairly specific feature of P.vivax that is helpful to indicate this diagnosis. The form develops as the parasites mature and early signs may be seen in early trophozoites. Additional images A A B B Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B) Additional images Pigment in different stages of parasite development Gametocyte P.malariae Schizont P.ovale Trophozoite P.ovale Gametocyte P.falciparum

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 |style = "font-size:110%; color:black; background: gainsboro |'''Navigation'''</br>
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-|<span style="font-size:110%">>[[Plasmodium_falciparum:_Morphology|Previous Page]]''</span></br>
+|<span style="font-size:110%">>[[Plasmodium_vivax:_Morphology|Previous Page]]''</span></br>
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 {| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"
-|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>'''Malaria Pigment''' (haemozoin)</span>
+|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>'''Amoeboid forms''' (haemozoin)</span>
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 <gallery mode="nolines" widths="220px" heights="220px" >
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-<span style=font-size:90%>'''Description'''</span>
+The late trophozoite of ''P.vivax'' becomes more solid, but with an irregular form that is said to resemble an amoeba with extended processes. Other features of the species will also be detected.
-<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemozoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.</span>
-<span style="font-size:90%>'''Species significance'''</span>
-<span style="font-size:90%>Pigment may vary in colour and may be clumped or scattered as individual small masses depending on species; in some instances this can help (most obviously in the central clump seen in the "daisy head" schizonts of ''P.malariae''). Generally however, the form of the pigment is less useful than other features in determining species.</span>
+<span style="color:navy>'''Species significance'''</span>
+A fairly specific feature of ''P.vivax'' that is helpful to indicate this diagnosis. The form develops as the parasites mature and early signs may be seen in early trophozoites.
+<span style="color:navy>'''Additional images'''</span>
+<gallery mode="nolines" widths="220px" heights="220px" >
+File:MAm1.jpg|A|link={{filepath:MAm1.jpg}}
+File:MAm3.jpg|B|link={{filepath:MAm3.jpg}}
+</gallery>
+Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B)
+----

Amoeboid form main: Difference between revisions

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Revision as of 18:14, 12 December 2024