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Plasmodium malariae: Morphology: Difference between revisions

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<span style="font-size:120%; color:black">''' ''Plasmodium malariae'' '''</br></span>
<span style="font-size:120%; color:black">''' ''Plasmodium malariae'' '''</br></span>
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<span style="font-size:90%">''P. malariae'' infection overlaps geographically with the distribution of ''P.falciparum'' in areas that include sub-Saharan Africa, Southeast Asia, Indonesia, the western Pacific and in areas of the Amazon Basin of South America.</span>
<span style="font-size:90%">''P. malariae'' infection overlaps geographically with the distribution of ''P.falciparum'' in areas that include sub-Saharan Africa, Southeast Asia, Indonesia, the western Pacific and in areas of the Amazon Basin of South America.</span>
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</br><span style="font-size:120%">The early trophozoite</span></br>
</br><span style="font-size:110%">'''The early trophozoite'''</span></br>
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</br><span style="font-size:130%">The late trophozoite</span>
</br><span style="font-size:110%">'''The late trophozoite'''</span>
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</br><span style="font-size:130%">The schizont</span></br>
</br><span style="font-size:110%">'''The schizont'''</span></br>
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</br><span style="font-size:130%">The gametocyte</span></br>
</br><span style="font-size:110%">'''The gametocyte'''</span></br>
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Revision as of 11:06, 19 December 2024

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Plasmodium malariae


P. malariae infection overlaps geographically with the distribution of P.falciparum in areas that include sub-Saharan Africa, Southeast Asia, Indonesia, the western Pacific and in areas of the Amazon Basin of South America.




The early trophozoite


During this later growth stage the rings enlarge and begin to modify the erythrocyte, forming typical features of the species.

  • Small but well-formed rings are typically seen someimes with a central chromatin dot or elongation
  • Red cells are generally of normal size, though occasionally may have reduced volume
  • Pigment will not generally be present at this developmental stage





The late trophozoite


Text

  • Parasites are larger and may be elongated, sometimes forming a band across the infected red cell
  • Red cells remain round, but size is often reduced
  • cytoplasmic dots are uncommon but may be seen
  • Pigment can now be seen over the parasite surface





The schizont


Often present in the blood, these small schizont forms may have species-specific features.

  • These are often seen in this species – the number of individual merozoites is often low (around 8)
  • Mature schizonts may have a characteristic central area of clumped pigment with the merozoites arranged around this forming a “daisy head”
  • At this stage the erythrocyte is devoid of haemoglobin and the small size is readily detected





The gametocyte


The sexual replication form in this species tend to be small beat and round.

  • Gametocytes tend to be regular and round in shape.
  • The parasites are small and do not generally fill the erythrocyte
  • Haemoglobin is absent and pigment overlies the gametocyte