Synchronous parasite development: Difference between revisions
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|<span style="font-size:110%">>[[Plasmodium_falciparum:_Morphology|Return to previous page]]''</span></br> | |||
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|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>''' | |colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>'''Synchronous development of parasites'''</span> | ||
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<span style="font-size:90%>''The release of merozoites from mature schizonts also causes release | <span style="font-size:90%>''The release of merozoites from mature schizonts also causes release of pigment and other parasite material that can cause an abrupt immune activation and pyrexia''</span></br></br> | ||
<span style="font-size:90%>Therefore, when schizont release is synchronous it can lead to the recognised phenomena of periodic fevers: e.g. in ''P.falciparum'' infection untreated individuals may exhibit fever cycles,with a 48-hour cycle so the periodicity corresponding to periods of abrupt schizont release (“tertian malaria”). This is not absolute with some infections appearing synchronous and others not.</span> | <span style="font-size:90%>Therefore, when schizont release is synchronous it can lead to the recognised phenomena of periodic fevers: e.g. in ''P.falciparum'' infection untreated individuals may exhibit fever cycles,with a 48-hour cycle so the periodicity corresponding to periods of abrupt schizont release (“tertian malaria”). This is not absolute with some infections appearing synchronous and others not.</span> | ||
Latest revision as of 13:56, 17 March 2025
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| Synchronous development of parasites
In some malaria infections (particularly with P.falciparum or with P.knowlesi) there may be only a single parasite stage visible in blood – this is most often the early trophozoite stage. This process is partly a reflection of the interesting phenomenon of “synchronicity” of parasite development. P.falciparum commonly the sole parasite stage visible will be early trophozoites The release of merozoites from mature schizonts also causes release of pigment and other parasite material that can cause an abrupt immune activation and pyrexia |
