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Interpretation guide: SINGLE BAND tests

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Single band RDT tests



RESULT PATTERN 1FAILED TEST

No band appears in the control area (black arrow)

Irrespective of whether any other bands are present, this is always an invalid test: do not interpret. Report as failed test
Action:


RESULT PATTERN 2

The test has valid control line (black arrow) and an additional band in the species-specific area (red arrow)

Most likely interpretation: The species detected by the test is present and is the only malaria species infecting the individual

Less likely but possible interpretations:




RESULT PATTERN 3

The test has valid control line (black arrow) but there is no band in the species-specific area (red arrow)


Most likely interpretation: the species detected by the test is not present

Less likely but possible alternatives:

  • A faint band was present but not seen by observer
  • The species is present but not detected due to low parasite concentration [ Limits of detection ].
  • The species is present is but not detected for technical reasons [ Practical reasons for poor RDT performance ]
  • The species is present, but there is gene deletion of the target antigen (HRP2 tests) [ HRP2 gene deletion ]
  • The species is present but exceeds test capacity due to very high parasite Pyrome effect (mainly HRP2 tests) [ Prozone effect ]