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RDT test: antigens

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RDT Test antigens: review of advantages and disadvantages

Malaria-species-specific antigens used in RDT tests

Some antigens are specifically expressed in individual malaria species and can be used to identify them as part of RDT assays. Two proteins are used for this purpose and are widely employed in RDT assays. These are::

(1) Histidine-rich protein 2 (HRP2): An antigen that is specific for P.falciparum - Click for details of HRP2
(2) Forms of lactate dehydrogenase that are specific for either P.falciparum or P.vivax Click for details of PfLDH or PvLDH

Malaria-species-specific antigens used in RDT tests

Pan-specific antigens: these detect the presence of any malaria species
 Pan-specific antigens: Plasmodium lactate dehydrogenase or Plasmodium aldolase Click for details

[ Histidine-rich protein 2 (HRP2) ]
[ Species-specific forms of lactate dehydrogenase (PfLDH and PvLDH) ]
[ Pan-specific antigens in RDTs ]
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