Multiplexed detection strategies may be used in some circumstances to optimase performance for local need: (a) Where both P.falciparum and P.vivax are highly prevalent, tests may be compiled the identify each with specificity - P.falciparum (HRP2) and P.vivax (Pv-pLDH). This can offer some advantages in detecting dual infection by the two species when compared to using a pan-malarial antibody.
to distinguish between infections by P. falciparum and P. vivax.
Alternatively, tests can be multiplexed to select for Pf-pLDH and HRP2, which yields highly sensitive indications for falciparum malaria. [16] Multiplexed RDTs have also proven to be efficacious in discriminating between distinct diseases with non-specific symptomatic presentations.