Gallery of late trophozoites

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Gallery of Late Trophozoites

Late trophozoites often have "species-specific" changes that affect parasite, red cell shape or added dots. These may be very helpful in assigning diagnosis, although not all changes are fully specific to a single species.

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P.falciparum
The key features here are a slight thickening of ring forms but with the same appearances as early trophozoites. Additionally look for Maurer's dots and clefts appearning.

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  Two parasites, Maurer's dots

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  Double dot, Maurer's dots

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  Accolé and Maurer's dots

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  Accolé and Maurer's dots

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P.vivax
Rings begin as small forms, but become larger asociated with enlarged distorted red cells as they develop. Schüffner's dots will become present

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  Early ring form

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  Early ring form with faint dots

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  Llarge thickened ring trophozoite

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  Ring trophozoites, Schüffner's dots

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P.ovale
Ring form is retained but enlarges, red cells may develop fimbriation and enlarged ovoid form with visible James' dots.

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  Early ring form

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  Ring with dots/fimbriation

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  faint Ziemann's dots

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  Ring early ovoid change

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P.malariae
Infected red cells are generally infrequent. Early trophozoites are small in normal or small erythrocytes, and may have central chromatin dot, elongation or angular forms.

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  Ring form in small red cell

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  The central chromatin dot

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  Early elongation, Stinton's dots

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  Early angularity of form

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P.knowlesi
The early trophozoite may resembles P.falciparum and infected cells may be frequent. Later forms however begin to resemble parasites of P.malariae.

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  Fine early rings

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  Double dot (right)

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  Accolé form

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  Multiple infection

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