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Biology Quiz A Q3

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Biology Quiz A Q3


The Schizont developmental stage is the asexual replication stage that some trophozoites follow (others enter sexual development as gametocytes). During this stage the parasite undergoes a number of cycles of division to generate between 8 1n3 32 daughter parasites (1-3 on image) depending on species. The stage ends when the red cell membrane lyses releasing these daughter "merozoites" to enter other red cells (4&5 on image).

Concerning schizonts which statements are correct? (select all true statements)

The stage gives rise to gametocytes
Schizont release causes pyrexia
P.malariae" typically forms 32 merozoites
In P.falciparum they are rarely seen
The stage is morphologically variable


Explanation of correct answer (click "Expand")
Short answer taken from section "Microscopy vs RDT" (see the section for full details and links).

In ideal conditions a well-trained microscopist with experience in malaria, viewing a well-prepared thick blood film using a good quality microscope may detect with equal or better sensitivity than an RDT test.

In less ideal conditions where equipment, staining quality, or microscopic experience is less good, then RDTs may have equivalent or superior sensitivity to microscopy (including many malarial endemic regions where microscopy may be unavailable or where the sensitivity of microscopy is limited by training, equipment or facilities). RDTs aso provide a more rapid turnaround time allowing emergency use and rapid decision-making.


For species identification thin films are preferred to thick films or RTDS (including mixed infections), as they also allow more accurate identification of sepecies and the % of infected red-cells (for P.falciparum or P.knowlesi).


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