RDT Quiz A Q4

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RDT Quiz A Q4 Shown below is an RDT test. This uses a pan-malarial antibody (labelled Pan) and a P.falciparum species-specific antibody (labelled Sp). The test has been used to assess a patient and the positive bands are shown on the figure. Which of the following interpretions can reasonably be made? (select one or more options) 1. Consistent with a single species P.falciparum infection 2. Consistent with a single species non-P.falciparum infection 3. Consistent with a dual species infection including P.falciparum 4. Consistent with a dual species infection not including P.falciparum 5. Suggests P.falciparum with HRP2 gene-deletion 6. An unreportable test Explanation of correct answer (click "Expand") Most likely interpretation: The single species detected by the species specific band is present (this same species is also detected the pan-malaria band) Less likely but possible interpretations: There are two species present in the sample (likelihood depends on country of origin, but is less likely) [ Co-infection with two species ] There is a false positive result causing both bands (unlikely) [ False positive reaction in RDT tests ] Go to next question (5 of 5)