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RDT test: antigens: Difference between revisions

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<span style="font-size:90%">>>This page: '''The RDT antigens'''</span>
<span style="font-size:90%">>>This page: '''The RDT antigens'''</span>
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<span style="font-size:160%; color:navy">RDT Test antigens: advantages and disadvantages</br></span>
<span style="font-size:160%; color:navy">RDT Test antigens: review of advantages and disadvantages</br></span>
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(1) Histidine-rich protein 2 (HRP2): An antigen that is specific for ''P.falciparum'' - [[Histidine-rich protein 2 (HRP2)|Click for details of HRP2]]</br>
(1) Histidine-rich protein 2 (HRP2): An antigen that is specific for ''P.falciparum'' - [[Histidine-rich protein 2 (HRP2)|Click for details of HRP2]]</br>
(2) Forms of lactate dehydrogenase that are specific for either ''P.falciparum'' or ''P.vivax''  [[Species-specific forms of lactate dehydrogenase (PfLDH and PvLDH)|Click for details of PfLDH or PvLDH]]</br></br>
(2) Forms of lactate dehydrogenase that are specific for either ''P.falciparum'' or ''P.vivax''  [[Species-specific forms of lactate dehydrogenase (PfLDH and PvLDH)|Click for details of PfLDH or PvLDH]]</br></br>
'''Malaria-species-specific antigens used in diagnosis'''</br></br>
Pan-specific antigens:''' these detect the presence of any malaria species</span></br>
Pan-specific antigens:''' these detect the presence of any malaria species</span></br>
Pan-specific antigens: Plasmodium lactate dehydrogenase or Plasmodium aldolase [[Pan-specific antigens in RDTs|Click for details]]
Pan-specific antigens: Plasmodium lactate dehydrogenase or Plasmodium aldolase [[Pan-specific antigens in RDTs|Click for details]]

Revision as of 16:19, 2 October 2024

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RDT Test antigens: review of advantages and disadvantages

Malaria-species-specific antigens used in diagnosis

Some antigens are specifically expressed in individual malaria species and can be used to identify them as part of RDT assays. Two proteins are used for this purpose and are widely employed in RDT assays. These are::

(1) Histidine-rich protein 2 (HRP2): An antigen that is specific for P.falciparum - Click for details of HRP2
(2) Forms of lactate dehydrogenase that are specific for either P.falciparum or P.vivax Click for details of PfLDH or PvLDH

Malaria-species-specific antigens used in diagnosis

Pan-specific antigens: these detect the presence of any malaria species
 Pan-specific antigens: Plasmodium lactate dehydrogenase or Plasmodium aldolase Click for details

[ Histidine-rich protein 2 (HRP2) ]
[ Species-specific forms of lactate dehydrogenase (PfLDH and PvLDH) ]
[ Pan-specific antigens in RDTs ]
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