RDT test: antigens: Difference between revisions

Revision as of 16:18, 2 October 2024

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RDT Test antigens: advantages and disadvantages

Malaria-species-specific antigens used in diagnosis Some antigens are specifically expressed in individual malaria species and can be used to identify them as part of RDT assays. Two proteins are used for this purpose and are widely employed in RDT assays. These are:: (1) Histidine-rich protein 2 (HRP2): An antigen that is specific for P.falciparum - Click for details of HRP2 (2) Forms of lactate dehydrogenase that are specific for either P.falciparum or P.vivax Click for details of PfLDH or PvLDH Pan-specific antigens: these detect the presence of any malaria species Pan-specific antigens: Plasmodium lactate dehydrogenase or Plasmodium aldolase Click for details [ Histidine-rich protein 2 (HRP2) ] [ Species-specific forms of lactate dehydrogenase (PfLDH and PvLDH) ] [ Pan-specific antigens in RDTs ]

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 '''Malaria-species-specific antigens used in diagnosis'''</br></br>
-The following antigens are specific for individual malaria species:</br></br>
+Some antigens are specifically expressed in individual malaria species and can be used to identify them as part of RDT assays. Two proteins are used for this purpose and are widely employed in RDT assays. These are::</br></br>
 (1) Histidine-rich protein 2 (HRP2): An antigen that is specific for ''P.falciparum'' - [[Histidine-rich protein 2 (HRP2)|Click for details of HRP2]]</br>
 (2) Forms of lactate dehydrogenase that are specific for either ''P.falciparum'' or ''P.vivax''  [[Species-specific forms of lactate dehydrogenase (PfLDH and PvLDH)|Click for details of PfLDH or PvLDH]]</br></br>