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False positive reaction in RDT tests: Difference between revisions

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'''Navigation'''</br>
'''Navigation'''</br>
[[Interpretation guide: SINGLE BAND tests|Go Back]]
<span style="font-size:90%">[[MalariaETC Index|Main Malaria Index]]''</span></br>
<span style="font-size:90%">>[[Rapid diagnostic tests (RDTs)|RDT main page]]''</span></br>
<span style="font-size:90%">>>[[Interpretation guide: SINGLE BAND tests|Single Band Tests]]''</span></br>
<span style="font-size:90%">>>>Current page: '''Reasons for Test Failure'''</span>
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'''Cross-reactive antibodies'''
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|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>'''Cross-reactive antibodies'''


Cross-reactive antibodies may cause a "false positive" result by forming an immune complex with labelled test antibodies and the detection line that causes a band to appear in the test area.  
Cross-reactive antibodies may cause a "false positive" result by forming an immune complex with labelled test antibodies and the detection line that causes a band to appear in the test area.  

Revision as of 12:30, 30 September 2024


Navigation
Main Malaria Index
>RDT main page
>>Single Band Tests
>>>Current page: Reasons for Test Failure


Cross-reactive antibodies

Cross-reactive antibodies may cause a "false positive" result by forming an immune complex with labelled test antibodies and the detection line that causes a band to appear in the test area.

These cross-reactive antibodies arise following other infection (usually tropical organisms), but may also be polyreactive antibodies found in individuals in the general population, particularly rheumatoid factor (RF) or human anti-mouse (HAMA). The frequency with which such reactions occur depends considerably on the test manufacturer.