Emerging strategies and options: Difference between revisions

Revision as of 20:56, 27 September 2024

EXTRA Emerging Strategies for RDT design Multiplexed detection strategies may be used in some circumstances to optimase performance for local need: (a) Where both P.falciparum and P.vivax are highly prevalent, then tests with specificity for each species may prove valuable - P.falciparum (HRP2) and P.vivax (Pv-pLDH) may be combined with or without a pen-specific antibody. This can offer some advantages in detecting dual infection by the two species. (b) Where HRP2 deletion are frequent, they may cause a high risk for test failure, tests multiplexed to select for Pf-pLDH and HRP2 may improve detection in these circumstances.

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-|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>'''EXTRA'''</br><span style="color:navy>Emerging Strategies for RDT design'''</span>
+|colspan="1" style = "font-size:120%; color:black; background: FFFAFA"|<span style="color:black>'''EXTRA'''</br><span style="color:navy>Emerging Strategies for RDT design'''</span>
 <span style="font-size:90%">'''Multiplexed detection strategies''' may be used in some circumstances to optimase performance for local need:</br></br> (a) Where both ''P.falciparum'' and ''P.vivax'' are highly prevalent, then tests with specificity for each species may prove valuable -  ''P.falciparum'' (HRP2) and ''P.vivax'' (Pv-pLDH) may be combined with or without a pen-specific antibody. This can offer some advantages in detecting dual infection by the two species.</br></br>(b) Where HRP2 deletion are frequent, they may cause a high risk for test failure, tests multiplexed to select for Pf-pLDH and HRP2 may improve detection in these circumstances.
 |}