Interpretation guide: SINGLE BAND tests: Difference between revisions
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{| class="wikitable" style="border-style: none; border-width: 2px; border-color: gainsboro; color:black" | {| class="wikitable" style="border-style: none; border-width: 2px; border-color: gainsboro; color:black" | ||
|colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''RESULT 1 | |colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''RESULT PATTERN 1 | ||
''' | ''' | ||
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File:RDT_single_no band+.jpg|<span style="font-size:90%"></span>|link={{filepath:RDT_single_no band+.jpg}} | File:RDT_single_no band+.jpg|<span style="font-size:90%"></span>|link={{filepath:RDT_single_no band+.jpg}} | ||
</gallery></br> | </gallery></br> | ||
<span style="font-size:90%">Irrespective of whether any other bands are present, this is always an invalid test: '''do not interpret'''</br>Action:</br></span> | <span style="font-size:90%">Irrespective of whether any other bands are present, this is always an invalid test: '''do not interpret.''' Report as failed test</br>Action:</br></span> | ||
*<span style="font-size:90%">Repeat the test</br></span> | *<span style="font-size:90%">Repeat the test</br></span> | ||
*<span style="font-size:90%">Consider the reasons for [[Practical reasons for test failure|test failure]]</span> | *<span style="font-size:90%">Consider the reasons for [[Practical reasons for test failure|test failure]]</span> | ||
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|colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''RESULT 2''' | |colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''RESULT PATTERN 2''' | ||
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|colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''RESULT 3''' | |colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''RESULT PATTERN 3''' | ||
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<span style="font-size:90%">The test has '''valid control line''' (black arrow) but there is ''' | <span style="font-size:90%">The test has '''valid control line''' (black arrow) but there is '''no band in the species-specific area''' (red arrow)</span> | ||
<gallery mode="nolines" widths=100px heights=200px> | <gallery mode="nolines" widths=100px heights=200px> | ||
File:RDT_single_no band.jpg|<span style="font-size:90%"></span>|link={{filepath:RDT_single_no band.jpg}} | File:RDT_single_no band.jpg|<span style="font-size:90%"></span>|link={{filepath:RDT_single_no band.jpg}} | ||
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*A faint band was present but not seen by observer* | *A faint band was present but not seen by observer* | ||
*The species is present but not detected due to low parasite concentration (link to reasons) | *The species is present but not detected due to low parasite concentration (link to reasons) | ||
*The species is present is but not detected for technical reasons | |||
*The species is present, but there is gene deletion of the target antigen (HRP2 tests) | *The species is present, but there is gene deletion of the target antigen (HRP2 tests) | ||
*The species is present but exceeds test capacity due to very high parasite Pyrome effect (mainly HRP2 tests) | *The species is present but exceeds test capacity due to very high parasite Pyrome effect (mainly HRP2 tests) | ||
Revision as of 18:54, 15 September 2024
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| RESULT PATTERN 1
|
No band appears in the control area (black arrow)
Irrespective of whether any other bands are present, this is always an invalid test: do not interpret. Report as failed test
Action:
- Repeat the test
- Consider the reasons for test failure
| RESULT PATTERN 2 |
The test has valid control line (black arrow) and an additional band in the species-specific area (red arrow)
Most likely interpretation: The species detected by the test is present and is the only malaria species infecting the individual
Less common but possible interpretations:
- There is a dual-species infection (a second species cannot be detected by single band kits)
- The patient recently received successful treatment, but the antigen has not yet cleared
- The "specific band" is a false positive result (infrequent but observed)
| RESULT PATTERN 3 |
The test has valid control line (black arrow) but there is no band in the species-specific area (red arrow)
Most likely interpretation: the species detected by the test is not present
Possible alternatives:
- A faint band was present but not seen by observer*
- The species is present but not detected due to low parasite concentration (link to reasons)
- The species is present is but not detected for technical reasons
- The species is present, but there is gene deletion of the target antigen (HRP2 tests)
- The species is present but exceeds test capacity due to very high parasite Pyrome effect (mainly HRP2 tests)