Emerging strategies and options: Difference between revisions

Revision as of 14:37, 13 September 2024

Navigation
Go Back

Emerging Strategies Multiplexed detection strategies may be used in some circumstances to optimase performance for local need: (a) Where both P.falciparum and P.vivax are highly prevalent, tests may be compiled the identify each with specificity - P.falciparum (HRP2) and P.vivax (Pv-pLDH). This can offer some advantages in detecting dual infection by the two species when compared to using a pan-malarial antibody. to distinguish between infections by P. falciparum and P. vivax. Alternatively, tests can be multiplexed to select for Pf-pLDH and HRP2, which yields highly sensitive indications for falciparum malaria. [16] Multiplexed RDTs have also proven to be efficacious in discriminating between distinct diseases with non-specific symptomatic presentations.

@@ Line 9: / Line 9: @@
-<span style="font-size:90%">Multiplexed detection strategies may be used in some circumstances to optimase performance for local need:</br>(a) Where both ''P.falciparum'' and ''P.vivax'' are highly prevalent, tests may be compiled the identify each with specificity -  ''P.falciparum'' (HRP2) and ''P.vivax'' (Pv-pLDH). This can offer some advantages in detecting dual infection by the two species when compared to using a pan-malarial antibody.
+<span style="font-size:90%">'''Multiplexed detection strategies may be used in some circumstances to optimase performance for local need:'''</br></br>(a) Where both ''P.falciparum'' and ''P.vivax'' are highly prevalent, tests may be compiled the identify each with specificity -  ''P.falciparum'' (HRP2) and ''P.vivax'' (Pv-pLDH). This can offer some advantages in detecting dual infection by the two species when compared to using a pan-malarial antibody.
 to distinguish between infections by P. falciparum and P. vivax.
 Alternatively, tests can be multiplexed to select for Pf-pLDH and HRP2, which yields highly sensitive indications for falciparum malaria. [16] Multiplexed RDTs have also proven to be efficacious in discriminating between distinct diseases with non-specific symptomatic presentations.