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Revision as of 17:50, 16 December 2024
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| Cytoplasmic dots
The dots of different species represent parasite proteins that modify red cell function in a range of ways to support parasite development, immun evasion or virulence. Their precise functions are ill defined, but their appearances have value in distinguishing the different species of parasite. The dots require a well-stained specimen to be easily seen! Schüffner's dots (P.vivax) and James' dots) (P.ovale) are very numerous red/purple dots that become apparent during the early trophzoite as faint dots, then more easily seen in later developmental stages. These two forms of dots are morphologically indistinguishable as frequent evenly-distrubuted round dots of similar size. Maurer's dots and clefts (P.falciparum) are blue/purple coloured and are not acquired until the late trophozoite stage of parasite development, are fewer in number than Schüffner's or James' dots and may appear as dots, clefts or plaques. The Sinton and Mulligan's stippling of P.knowlesi may appear similar to Maurer's dots. Ziemann's stippling (P.malariae) Is not usully seen, but when present appears as faint fine (and inconspicuous) dots in cytoplasm of some ifected erythrocytes. |
