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! colspan="1" | <span style="font-size:90%">Explanation of correct answer (click "Expand")
! colspan="1" | <span style="font-size:90%">Explanation of correct answer (click "Expand")
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|<span style="font-size:90%">'Short answer taken from section "Multi-line RDT Interpretation" (see the section for full details and links)''.</br></br>'''When no band appears in the control area (black arrow) the test is ALWAYS invalid</span>:'''</br></br>
|<span style="font-size:90%">'Short answer taken from section "Multi-line RDT Interpretation" (see the section for full details and links)''.</br></br><span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemozoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development. When schizonts rupture to release their daughter parasites, the pigment is also released and is takn up by phagocytes.</span>
 
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File:RDT_multi_fail1.jpg|<span style="font-size:90%"></span>|link={{filepath:RDT_multi_fail1.jpg}}
File:RDT_multi_fail2.jpg|<span style="font-size:90%"></span>|link={{filepath:RDT_multi_fail1.jpg}}
File:RDT_multi_fail3.jpg|<span style="font-size:90%"></span>|link={{filepath:RDT_multi_fail1.jpg}}
File:RDT_multi_fail4.jpg|<span style="font-size:90%"></span>|link={{filepath:RDT_multi_fail1.jpg}}
</gallery>
<span style="font-size:90%">Irrespective of whether any other bands are present, this is always an invalid test: '''do not interpret.''' Report as failed test</br>Action:</span>
*<span style="font-size:90%">Repeat the test</br></span>
*<span style="font-size:90%">Consider the reasons for test failure</span>
</br>
</br>
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{| class="wikitable" style="width:300px; border-left:solid 4px navy;border-right:solid 4px navy;border-top:solid 4px navy;border-bottom:solid 4px navy; font-size:100%; color:navy; align:center"
|colspan="1" style = "font-size:90%; color:black|<span style="color:black>[[Biology_Quiz_A_Q3|<span style="font-size:90%">Go to next question (3 of 5)]]</span>
|colspan="1" style = "font-size:90%; color:black|<span style="color:black>[[Biology_Quiz_A_Q3|<span style="font-size:90%">Go to next question (3 of 5)]]</span>

Revision as of 15:38, 27 November 2024

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RDT Quiz A Q2


During the trophozoite stage of parasite growth there are many changes to both parasite and the red cell it is contained in. All species dorm malarial pigment (haemozoin) as they develop as it is essential to their safe development.

Which of the following are true of malarial pigment? (select one or more options)

It is formed as part of "haem" digestion
It is formed as part of "globin digestion"
P.malariae does not form pigment
Iron is an important part of malaria pigment
Pigment may also be found in phagocytes
It is most obvious in early trophozoites


Explanation of correct answer (click "Expand")
'Short answer taken from section "Multi-line RDT Interpretation" (see the section for full details and links).

During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemozoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development. When schizonts rupture to release their daughter parasites, the pigment is also released and is takn up by phagocytes.


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