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|colspan="1" style = "font-size:130%; color:black; background: FFFAFA"|<span style="color:black>'''RDT Quiz A Q2'''</span>
|colspan="1" style = "font-size:130%; color:black; background: FFFAFA"|<span style="color:black>'''RDT Quiz A Q2'''</span>
</br><span style="font-size:90%">Shown below is an RDT test. This uses a pan-malarial antibody (labelled Pan) and a ''P.falciparum'' species-specific antibody (labelled Sp). The test has been used to assess a patient and the positive bands are shown on the figure.</span>
</br><span style="font-size:90%">RDT tests use specific antibodies to identify the malaria species. Users often believe that these tests  are equally effective for diagnosing all species, but this is not true.</br></br></span>
<gallery mode="nolines" widths=80px heights=250px>
<gallery mode="nolines" widths=80px heights=250px>
File:RDT multi fail4.jpg|link={{filepath:RDT multi fail4}.jpg}
File:RDT multi fail4.jpg|link={{filepath:RDT multi fail4}.jpg}

Revision as of 14:22, 25 November 2024

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RDT Quiz A Q2


RDT tests use specific antibodies to identify the malaria species. Users often believe that these tests are equally effective for diagnosing all species, but this is not true.

RDT Quiz A Q1

For which malaria species do appropriate RDT tests have best sensitivity (make two selections)?

P.falciparum
P.vivax
P.ovale
P.malariae
P.knowlesi


Explanation of correct answer (click "Expand")
The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests (the specific section in the main section provides more detail).

P.falciparum
At high parasitaemia expect high sensitivity (90-95%). This declines when parasite levels are lower (45-70%)
P.vivax
Expect moderate to high sensitivity at high parasitaemia (70-90%). This declines markedly when parasite levels are lower (30-60%)
P.ovale & P.malarae
Generally sensitivity is poor (approximately half the sensitivity shown for P.vivax)
P.knowlesi
Reports suggest variable sensitivity that may depend on test used, RDTs are reported tp detect this species well when parasitaemia is high.
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