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RDT Quiz A Q1: Difference between revisions

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! colspan="1" | Explanation of correct answer (click "Expand")
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|</b><span style="font-size:90%">The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests when suitable species-specific together with pan-malarial antibodies are used. The table is only a broad summary. </span></br></br>
|</b><span style="font-size:90%">The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests (the specific section in the main section provides more detail).</span></br></br>


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<span style="font-size:80%">Notes:</br></span>
<span style="font-size:80%"><sup>1</sup> HRP2 mutation mean that in some geographical areas the diagnostic sensitivity may be significantly lower for HRP2-based tests (see below)</br></span>
<span style="font-size:80%"><sup>2</sup> Low parasite number is considered as (<1000 parasites/μL) a level that may cause symptoms in children or non-immune travellers</br></span>
<span style="font-size:80%"><sup>3</sup> There have been relatively few studies with this species so caution is required in RDT interpretation</br></span>
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|colspan="1" style = "font-size:90%; color:black|<span style="color:black>[[RDT_Quiz_A_Q2|Go to next question (2 of 5)]]</span>
|colspan="1" style = "font-size:90%; color:black|<span style="color:black>[[RDT_Quiz_A_Q2|Go to next question (2 of 5)]]</span>

Revision as of 19:47, 23 November 2024

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RDT Quiz A Q2

For which malaria species do appropriate RDT tests have best sensitivity (make two selections)?

P.falciparum
P.vivax
P.ovale
P.malariae
P.knowlesi


Explanation of correct answer (click "Expand")
The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests (the specific section in the main section provides more detail).

P.falciparum1
At high parasitaemia expect high sensitivity (90-95%). This declines when parasite levels are lower (45-70%)2
P.vivax
Expect moderate to high sensitivity at high parasitaemia (70-90%). This declines markedly when parasite levels are lower (30-60%)2
P.ovale & P.malarae
Generally sensitivity is poor (approximately half the sensitivity shown for P.vivax)
P.knowlesi3
Reports suggest variable sensitivity that may depend on test used, RDTs are reported tp detect this species well when parasitaemia is high.
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