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RDT detection sensitivity for different species: Difference between revisions

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|colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''HOW WELL ARE DIFFERENT SPECIES DETECTED?'''
|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>'''Cytoplasmic dots'''</span>
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</b><span style="font-size:90%">The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests when suitable species-specific together with pan-malarial antibodies are used. The table is only a broad summary. Users are advised to understand the characteristics of the test they use including the merits of the antibodies employed in their test (see section below) </span></br></br>
</b><span style="font-size:90%">The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests when suitable species-specific together with pan-malarial antibodies are used. The table is only a broad summary. Users are advised to understand the characteristics of the test they use including the merits of the antibodies employed in their test (see section below) </span></br></br>

Revision as of 12:41, 23 November 2024


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Cytoplasmic dots

The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests when suitable species-specific together with pan-malarial antibodies are used. The table is only a broad summary. Users are advised to understand the characteristics of the test they use including the merits of the antibodies employed in their test (see section below)

P.falciparum1
At high parasitaemia expect high sensitivity (90-95%). This declines when parasite levels are lower (45-70%)2
P.vivax
Expect moderate to high sensitivity at high parasitaemia (70-90%). This declines markedly when parasite levels are lower (30-60%)2
P.ovale & P.malarae
Generally sensitivity is poor (approximately half the sensitivity shown for P.vivax)
P.knowlesi3
Reports suggest variable sensitivity that may depend on test used, RDTs are reported tp detect this species well when parasitaemia is high.