RDT detection sensitivity for different species: Difference between revisions
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Revision as of 12:39, 23 November 2024
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| HOW WELL ARE DIFFERENT SPECIES DETECTED? |
The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests when suitable species-specific together with pan-malarial antibodies are used. The table is only a broad summary. Users are advised to understand the characteristics of the test they use including the merits of the antibodies employed in their test (see section below)
| P.falciparum1 |
|---|
| At high parasitaemia expect high sensitivity (90-95%). This declines when parasite levels are lower (45-70%)2 |
| P.vivax |
| Expect moderate to high sensitivity at high parasitaemia (70-90%). This declines markedly when parasite levels are lower (30-60%)2 |
| P.ovale & P.malarae |
| Generally sensitivity is poor (approximately half the sensitivity shown for P.vivax) |
| P.knowlesi3 |
| Reports suggest variable sensitivity that may depend on test used, RDTs are reported tp detect this species well when parasitaemia is high. |