RDT detection sensitivity for different species: Difference between revisions
From MalariaETC
No edit summary Tag: Reverted |
No edit summary Tag: Manual revert |
||
| Line 2: | Line 2: | ||
---- | ---- | ||
<span style="font-size:90%">>>[[Index|Back | <span style="font-size:90%">>>[[Index|Back]]''</span></br> | ||
---- | ---- | ||
Revision as of 12:36, 23 November 2024
>>Back
| HOW WELL ARE DIFFERENT SPECIES DETECTED? |
The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests when suitable species-specific together with pan-malarial antibodies are used. The table is only a broad summary. Users are advised to understand the characteristics of the test they use including the merits of the antibodies employed in their test (see section below)
| P.falciparum1 |
|---|
| At high parasitaemia expect high sensitivity (90-95%). This declines when parasite levels are lower (45-70%)2 |
| P.vivax |
| Expect moderate to high sensitivity at high parasitaemia (70-90%). This declines markedly when parasite levels are lower (30-60%)2 |
| P.ovale & P.malarae |
| Generally sensitivity is poor (approximately half the sensitivity shown for P.vivax) |
| P.knowlesi3 |
| Reports suggest variable sensitivity that may depend on test used, RDTs are reported tp detect this species well when parasitaemia is high. |