General and specific limitations of RDT tests

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Detection limits of RDTs RDT evaluationby WHO requires tests to identify 75% of cases at parasite concentration of 200 parasites/μl. It is important to note however that fevers may be present at lower parasite levels (particularly in non-immune travellers). Therefore, for the detection of P.falciparum using approved tests, the lower limits of detection are not sufficient to confidently exclude infection. For non-falciparum species tests are less reliable. These limitations are also summarised in the Table on the main page.