Co-infection with two species: Difference between revisions
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Mixed-species malaria infections certainly occur. Their precise frequency will vary according to the case-mix in the area concerned. | <span style="font-size:90%">Mixed-species malaria infections certainly occur. Their precise frequency will vary according to the case-mix in the area concerned.</br></br>In endemic areas where multiple malarial species circulate estimates of prevalence may be as high as 30%, but in other areas this is far lower and would often be regarded as forming fewer than 5% of infections.</span> | ||
In endemic areas where multiple malarial species circulate estimates of prevalence may be as high as 30%, but in other areas this is far lower and would often be regarded as forming fewer than 5% of infections. | |||
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Recogition by morphology requires the presence of parasite forms that have recognisable species-specific features for two separate species. This may sometimes be easy, but can be challenging when one species predominates. Some examples are shown below:</br></br> | <span style="font-size:90%">Recogition by morphology requires the presence of parasite forms that have recognisable species-specific features for two separate species. This may sometimes be easy, but can be challenging when one species predominates. Some examples are shown below:</br></br></span> | ||
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Image A: two gametocytes in separate red cells. These clearly have different appearances - one has the elongated and curved form typical of ''P.falciparum'', while the second is "round" with visible | <span style="font-size:90%">'''Image A''': two gametocytes in separate red cells. These clearly have different appearances - one has the elongated and curved form typical of ''P.falciparum'', while the second is "round" with visible round bametocytecytoplasmic dots and fimbriation of the red cell - appearances of ''P.ovale''.</br<</br>'''Image B''': a large parasite within the red cell is clearly seen and has the chacteristics of a microgametocyte of ''P.ovale'', but note also a small fine early "double dot" ring form of ''P.falciparum'' that is within the same erythocyte - an unusual "dual-parasite" erythrocyte!</span> | ||
Revision as of 13:29, 21 November 2024
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Recogition by morphology requires the presence of parasite forms that have recognisable species-specific features for two separate species. This may sometimes be easy, but can be challenging when one species predominates. Some examples are shown below:
Image A: two gametocytes in separate red cells. These clearly have different appearances - one has the elongated and curved form typical of P.falciparum, while the second is "round" with visible round bametocytecytoplasmic dots and fimbriation of the red cell - appearances of P.ovale.</br< |
