RDT test: formats of tests: Difference between revisions
From MalariaETC
(Created page with "{| class="wikitable" style="border-style: none; border-width: 2px; border-color: gainsboro; color:black" |colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''TEST FORMATS''' |} <span style="font-size:90%">'''Single test-band RDT tests'''</br></span> <gallery mode="nolines" widths=300px heights=80px> File:RDT_single.jpg|<span style="font-size:90%"></span>|link={{filepath:RDT_single.jpg}} </gallery></br> <span style="font-size:90%">This test form...") |
No edit summary |
||
| Line 29: | Line 29: | ||
<span style="font-size:90%">Most often one band is a species-specific antibody that identifies the dominant (or most important) species for the selected region. The second band generally employs a pan-malaria antibody that ''may' detect other species. The most frequent format is ''P.falciparum''-specific combined with a ''Pan-malaria-specific'' antibdy.</br></br> This format can be very effective providing its' limitations are understood by users. In particular the poor sensitivity of pan-malarial antibodies for some species. | <span style="font-size:90%">Most often one band is a species-specific antibody that identifies the dominant (or most important) species for the selected region. The second band generally employs a pan-malaria antibody that ''may' detect other species. The most frequent format is ''P.falciparum''-specific combined with a ''Pan-malaria-specific'' antibdy.</br></br> This format can be very effective providing its' limitations are understood by users. In particular the poor sensitivity of pan-malarial antibodies for some species. | ||
[[less common strategies]] | |||
Revision as of 10:41, 19 September 2024
| TEST FORMATS |
Single test-band RDT tests
This test format usually uses the HRP2 antigen to detect P.falciparum and offers particular advantages:
- simplicity of interpretation
- lower production cost
- stability for storage and transport
- valuable where a single malaria species dominates.
Use: The single species test for P.falciparum is very useful in Africa areas where infections with this species account for more than 95% of infections and may be used where technical expertise is less available. However, this is at the cost missing less prevelant species, and the lack of a pan-malaria antibody means that cases with HRP2-gene delection may be missed.
Multi-band RDT tests
These use two (or occasionally more) test bands together with a control band.
Most often one band is a species-specific antibody that identifies the dominant (or most important) species for the selected region. The second band generally employs a pan-malaria antibody that may' detect other species. The most frequent format is P.falciparum-specific combined with a Pan-malaria-specific antibdy.
This format can be very effective providing its' limitations are understood by users. In particular the poor sensitivity of pan-malarial antibodies for some species.