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Practical reasons for test failure: Difference between revisions

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'''Navigation'''</br>
'''Navigation'''</br>
[[Interpretation guide: SINGLE BAND tests|Go Back]]
<span style="font-size:90%">[[MalariaETC Index|Main Malaria Index]]''</span></br>
<span style="font-size:90%">[[Rapid diagnostic tests (RDTs)|RDT main page]]''</span></br>
<span style="font-size:90%">>[[RDT_test:_formats_of_tests|RDT Test Design]]''</span></br>
<span style="font-size:90%">>>Current page: '''Reasons for Test Failure'''</span>
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{| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; color:black"
|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>'''Practical considerations '''</span>
|colspan="1" style = "font-size:100%; color:blasck; background: FFFAFA"|<span style="color:navy>'''Practical considerations '''</span>


<span style="font-size:90%">Bibilography: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652944/], [https://www.who.int/teams/global-malaria-programme/case-management/diagnosis/rapid-diagnostic-tests]</span>
<span style="font-size:90%">Bibilography: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652944/], [https://www.who.int/teams/global-malaria-programme/case-management/diagnosis/rapid-diagnostic-tests]</span>

Revision as of 12:21, 30 September 2024


Navigation
Main Malaria Index
RDT main page
>RDT Test Design
>>Current page: Reasons for Test Failure


Practical considerations

Bibilography: [1], [2]


1. Selection and procurement of MDTs

(a) Quality of test design/production. There may be significant variation of performance between tests, users are advised to check test performance (see WHO testing information ref 2 above)
(b) Lot variability. Variability between different production batches has been observed and should be considered if RDT performance is less than expected.

2. Stability and storage issues

(a) RDTs typically have a shelf-life of 18–24 months providing storage is appropriateR.
(b) Tests can suffer degradation if stored in inappropriate heat or humidity: generally tests are stable in the range 2–30°C or higher, but these limits may be exceeded in many countries, and continuous product refrigeration to the point of use may not be guarenteed in developing countries.

3. Operator training

(a)Problems in test usage may include inappropriate placement of test reagents or blood sample on RDT.
(b)Poor interpretion of faint lines.
(c) Inadequate training or reference materials