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Interpretation guide: SINGLE BAND tests: Difference between revisions

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'''No band appears in the control area (black arrow)'''
'''No band appears in the control area''' (black arrow)


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</gallery></br>
</gallery></br>


Irrespective of whether any other bands are present, this is alwys an invalid test: '''do not interpret'''</br>
Irrespective of whether any other bands are present, this is always an invalid test: '''do not interpret'''</br>
Action:</br>  
Action:</br>  
*Repeat the test</br>
*Repeat the test</br>
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The test has '''valid control line''' (black arrow) and an '''additional band in the species-specific area''' (red arrow)
(pici)
(pici)


Most likely interpretation: The indicated species is present only</br></br>
Most likely interpretation: The indicated species is present and is the only malaria species</br></br>
Less common but possible interpretations:</br>
Less common but possible interpretations:</br>
*There is a dual-species infection (a second species will not be detected by single band kits)
*There is a dual-species infection (a second species cannot be detected by single band kits)
*The "specific band" observed represents a false positive reaction (infrequent but observed)
*The "specific band" is a false positive result (infrequent but observed)
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(2) No band present in species-specific area Most common: the species is not present Possible alternatives: A faint band was present but not seen by observer* The species is present but not detected due to low parasite concentration (link to reasons) The species is present but not detected for technical reasons The species is present, but there is gene deletion of the target antigen (HRP2 tests) The species is present but exceeds test capacity due to very high parasite Pyrome effect (mainly HRP2 tests)
(2) No band present in species-specific area Most common: the species is not present Possible alternatives: A faint band was present but not seen by observer* The species is present but not detected due to low parasite concentration (link to reasons) The species is present but not detected for technical reasons The species is present, but there is gene deletion of the target antigen (HRP2 tests) The species is present but exceeds test capacity due to very high parasite Pyrome effect (mainly HRP2 tests)

Revision as of 15:38, 15 September 2024


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RESULT 1

No band appears in the control area (black arrow)


Irrespective of whether any other bands are present, this is always an invalid test: do not interpret
Action:

  • Repeat the test
  • Consider the reasons for test failure

The test has valid control line and an additional band in the species-specific area

The test has valid control line (black arrow) and an additional band in the species-specific area (red arrow) (pici)

Most likely interpretation: The indicated species is present and is the only malaria species

Less common but possible interpretations:

  • There is a dual-species infection (a second species cannot be detected by single band kits)
  • The "specific band" is a false positive result (infrequent but observed)


(2) No band present in species-specific area Most common: the species is not present Possible alternatives: A faint band was present but not seen by observer* The species is present but not detected due to low parasite concentration (link to reasons) The species is present but not detected for technical reasons The species is present, but there is gene deletion of the target antigen (HRP2 tests) The species is present but exceeds test capacity due to very high parasite Pyrome effect (mainly HRP2 tests)