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Prozone effect: Difference between revisions

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|colspan="1" style = "font-size:110%; color:black; background: white"|<span style="color:navy>'''The prozone effect'''</span>
|colspan="1" style = "font-size:110%; color:black; background: white"|<span style="color:navy>''''''</span>




A very rare, but recognised effect, most often this affects HRP2 antigens and means that in very high parasitaemia (causing excess antigen), the formation of appropriate antibody-antigen complexes is prevented causing the test to appear negative.
The prozone effect is a very rare, but recognised effect, most often this affects HRP2 antigens and means that in very high parasitaemia (causing excess antigen), the formation of appropriate antibody-antigen complexes is prevented causing the test to appear negative.




[[Histidine-rich protein 2 (HRP2)|Return to HRP2 page]]
[[Histidine-rich protein 2 (HRP2)|Return to HRP2 page]]

Revision as of 14:23, 23 August 2024

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The prozone effect is a very rare, but recognised effect, most often this affects HRP2 antigens and means that in very high parasitaemia (causing excess antigen), the formation of appropriate antibody-antigen complexes is prevented causing the test to appear negative.


Return to HRP2 page