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Plasmodium knowlesi: Morphology: Difference between revisions

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(Created page with " ---- '''Geographical distribution''' Rarely, since it is acquired only from monkey host in forest or forest-fringe in S.E.Asia with no human to human spread It is important to recognise this parasite however, since it has rapid division (each 24 hours), and may have high-parasitaemia with the potential for rapidly developing life threatening disease. Detailed geographical information may be accessed here: [https://map.ox.ac.uk/country-profiles/#!/ Malaria Atlas Proj...")
 
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{| class="wikitable" style="width: 60%; border-style: none; border-width: 0px; border-color: gainsboro; color:black"
|style = "font-size:110%; color:black; background: gainsboro |'''Navigation'''</br>
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|<span style="font-size:110%">>[[MalariaETC Index|Main malaria Index]]''</span></br>
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|<span style="font-size:110%">>[[Species_identification:_summary_page|Main Species identification page]]''</span></br>
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<span style="font-size:120%; color:black">''' ''Plasmodium knowlesi'' '''</br></span>
'''Geographical distribution'''
</br>
 
<span style="font-size:90%">'''Geographical distribution: '''Rarely, since it is acquired only from monkey host in forest or forest-fringe in S.E.Asia with no human to human spread It is important to recognise this parasite however, since it has rapid division (each 24 hours), and may have high-parasitaemia with the potential for rapidly developing life threatening disease.</span>
Rarely, since it is acquired only from monkey host in forest or forest-fringe in S.E.Asia with no human to human spread It is important to recognise this parasite however, since it has rapid division (each 24 hours), and may have high-parasitaemia with the potential for rapidly developing life threatening disease.
 
Detailed geographical information may be accessed here: [https://map.ox.ac.uk/country-profiles/#!/ Malaria Atlas Project].
 


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Revision as of 09:57, 23 December 2024

Navigation
>Main malaria Index
>Main Species identification page

Plasmodium knowlesi

Geographical distribution: Rarely, since it is acquired only from monkey host in forest or forest-fringe in S.E.Asia with no human to human spread It is important to recognise this parasite however, since it has rapid division (each 24 hours), and may have high-parasitaemia with the potential for rapidly developing life threatening disease.


The early trophozoite


rleftt


  • Generally present and most resemble P.falciparum
  • Small (1/3 to 1/2 of erythrocyte) relatively fine
  • Occasionally non -vacuolated
  • Double dots may be seen often at opposite poles
  • Multiple infection is cells frequent, but accolé forms rare or absent
  • No size change, stippling or pigment at this stage



The late trophozoite


File:PKLT.jpg



  • Usually present and most closely resemble P.malariae
  • May be dense amoeboid or band-form, but generally retain a vacuole
  • Acquiring pigment at late stages, may be separate or clumped
  • Occasional sparse dots may seen (Sinton or Mulligan's stippling)
  • Red cell size generally unaffected



The schizont


leftt


  • Present in mast cases partly resemble P.malariae
  • Up to 16 merozoites (exceeds P.malariae)
  • Do not generally fill the erythrocyte,.may be irregular or grape-like.
  • Erythrocyte not enlarged may be a irregular.
  • Dots are often seen.




The gametocyte


File:PMG.jpg



  • Gametocytes tend to be regular and round in shape.
  • The parasites are small and do not generally fill the erythrocyte
  • Haemoglobin is absent and pigment overlies the gametocyte



Gallery

Click here to see gallery of Plasmodium malariae forms