Plasmodium malariae: Morphology: Difference between revisions
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<span style="font-size:90%">During this later growth stage the rings enlarge and begin to modify the erythrocyte, forming typical features of the species.</span> | <span style="font-size:90%">During this later growth stage the rings enlarge and begin to modify the erythrocyte, forming typical features of the species.</span> | ||
*<span style="font-size:90%">Small but well-formed rings are typically seen | *<span style="font-size:90%">Small but well-formed rings are typically seen sometimes with a [[Central_chromatin_dot_1|central chromatin dot]] or elongation | ||
*<span style="font-size:90%">Red cells are generally of normal size, though occasionally may have reduced volume | *<span style="font-size:90%">Red cells are generally of normal size, though occasionally may have reduced volume | ||
*<span style="font-size:90%">Pigment will not generally be present at this developmental stage | *<span style="font-size:90%">Pigment will not generally be present at this developmental stage | ||
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<span style="font-size:90%">Text</span> | <span style="font-size:90%">Text</span> | ||
*<span style="font-size:90%">Parasites | *<span style="font-size:90%">Parasites may be elongated, forming a [[Band_form_PM|band]] across the infected red cell | ||
*<span style="font-size:90%">Red cells remain round, but [[size is often reduced]] | *<span style="font-size:90%">Others spread to form an [[Anglular_form_PM|angular or basket form]] within the red cell | ||
*<span style="font-size:90%">cytoplasmic dots are uncommon but [[Ziemann's dots]] may be seen | *<span style="font-size:90%">Red cells remain round, but [[Size_and_shape_PM|red cell size is often reduced]] | ||
*<span style="font-size:90%"> | *<span style="font-size:90%">cytoplasmic dots are uncommon but [[Added_dots_PM|Ziemann's dots]] may be seen | ||
*<span style="font-size:90%">Pigment can now be seen over the parasite surface | |||
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Revision as of 12:45, 19 December 2024
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Plasmodium malariae
P. malariae infection overlaps geographically with the distribution of P.falciparum in areas that include sub-Saharan Africa, Southeast Asia, Indonesia, the western Pacific and in areas of the Amazon Basin of South America.
The early trophozoite
During this later growth stage the rings enlarge and begin to modify the erythrocyte, forming typical features of the species.
- Small but well-formed rings are typically seen sometimes with a central chromatin dot or elongation
- Red cells are generally of normal size, though occasionally may have reduced volume
- Pigment will not generally be present at this developmental stage
The late trophozoite
Text
- Parasites may be elongated, forming a band across the infected red cell
- Others spread to form an angular or basket form within the red cell
- Red cells remain round, but red cell size is often reduced
- cytoplasmic dots are uncommon but Ziemann's dots may be seen
- Pigment can now be seen over the parasite surface
The schizont
Often present in the blood, these small schizont forms may have species-specific features.
- These are often seen in this species – the number of individual merozoites is often low (around 8)
- Mature schizonts may have a characteristic central area of clumped pigment with the merozoites arranged to form a “daisy head” appearance
- At this stage the erythrocyte is devoid of haemoglobin and the small size is readily detected
The gametocyte
The sexual replication form in this species tend to be small beat and round.
- Gametocytes tend to be regular and round in shape.
- The parasites are small and do not generally fill the erythrocyte
- Haemoglobin is absent and scattered pigment overlies or surrounds the gametocyte