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| <span style="font-size:90%">[[Index|back]]</span></br>
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| {| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"
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| |colspan="1" style = "font-size:130%; color:black; background: FFFAFA"|<span style="color:black>'''RDT Quiz A'''</span>
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| <quiz display=simple>
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| {1. Which '''TWO''' malarial species are most likely to be detected when using an appropriate RDT test (make two selections)?
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| |type="[]"}
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| + ''P.falciparum''
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| + ''P.vivax''
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| - ''P.ovale''
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| - ''P.malariae''
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| </quiz>
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| {| class="mw-collapsible mw-collapsed wikitable"
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| ! colspan="1" | Explanation of correct answer (click "Expand")
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| |-
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| |</b><span style="font-size:90%">The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests when suitable species-specific together with pan-malarial antibodies are used. The table is only a broad summary. </span></br></br>
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| <div style="width:100%; font-size:90%;">
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| !colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%">''' ''P.falciparum<sup>1</sup> '''</br>
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| !colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">At high parasitaemia expect high sensitivity (90-95%). This declines when parasite levels are lower (45-70%)<sup>2</sup>
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| !colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%;">''' ''P.vivax'' '''</span></br>
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| !colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">Expect moderate to high sensitivity at high parasitaemia (70-90%). This declines markedly when parasite levels are lower (30-60%)<sup>2</sup>
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| !colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%;">''' ''P.ovale & P.malarae'' '''</span></br>
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| !colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">Generally sensitivity is poor (approximately half the sensitivity shown for ''P.vivax'')
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| !colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%;">''' ''P.knowlesi''<sup>3</sup> '''</span></br>
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| !colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">Reports suggest variable sensitivity that may depend on test used, RDTs are reported tp detect this species well when parasitaemia is high.
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| |}
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| </div>
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| <span style="font-size:80%">Notes:</br></span>
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| <span style="font-size:80%"><sup>1</sup> HRP2 mutation mean that in some geographical areas the diagnostic sensitivity may be significantly lower for HRP2-based tests (see below)</br></span>
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| <span style="font-size:80%"><sup>2</sup> Low parasite number is considered as (<1000 parasites/μL) a level that may cause symptoms in children or non-immune travellers</br></span>
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| <span style="font-size:80%"><sup>3</sup> There have been relatively few studies with this species so caution is required in RDT interpretation</br></span>
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| </br>
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| |}
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| |colspan="1" style = "font-size:100%; color:black; background-color:background: DDDDDD"|<span style="color:black>[[RDT_Quiz_A_Q2|Next question (of 5)]]</span>
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