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Dual species infection: Difference between revisions

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<span style="font-size:90%">'''Image A''': two gametocytes in separate red cells. These clearly have different appearances - one has the elongated and curved form typical of ''P.falciparum'', while the second is "round" with visible round bametocytecytoplasmic dots and fimbriation of the red cell - appearances of ''P.ovale''.</br<</br>'''Image B''': a large parasite within the red cell is clearly seen and has the chacteristics of a microgametocyte of ''P.ovale'', but note also a small fine early "double dot" ring form  of ''P.falciparum'' that is within the same erythocyte - an unusual "dual-parasite" erythrocyte!</span>
<span style="font-size:90%">'''Image A''': two gametocytes in separate red cells. These clearly have different appearances - one has the elongated and curved form typical of ''P.falciparum'', while the second is "round" with visible round cytoplasmic dots and fimbriation of the red cell - appearances of ''P.ovale''.</br<</br>'''Image B''': a large parasite within the red cell is clearly seen and has the chacteristics of a microgametocyte of ''P.ovale'', but note also a small fine early "double dot" ring form  of ''P.falciparum'' that is within the same erythocyte - an unusual "dual-parasite" erythrocyte!</span>

Latest revision as of 23:08, 17 March 2025

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Dual species infection


Mixed-species malaria infections certainly occur. Their precise frequency will vary according to the case-mix in the area concerned.

In endemic areas where multiple malarial species circulate estimates of prevalence may be as high as 30%, but in other areas this is far lower and would often be regarded as forming fewer than 5% of infections.

Recogition by morphology requires the presence of parasite forms that have recognisable species-specific features for two separate species. This may sometimes be easy, but can be challenging when one species predominates. Some examples are shown below:

  • A

    A

  • B

    B

Image A: two gametocytes in separate red cells. These clearly have different appearances - one has the elongated and curved form typical of P.falciparum, while the second is "round" with visible round cytoplasmic dots and fimbriation of the red cell - appearances of P.ovale.</br<
Image B: a large parasite within the red cell is clearly seen and has the chacteristics of a microgametocyte of P.ovale, but note also a small fine early "double dot" ring form of P.falciparum that is within the same erythocyte - an unusual "dual-parasite" erythrocyte!

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