Practical reasons for poor RDT performance: Difference between revisions
From MalariaETC
(Created page with "---- '''Navigation'''</br> Go Back ---- {| class="wikitable" style="border-style: solid; border-width: 4px; color:black" |colspan="1" style = "font-size:100%; color:black; background: FFFAFA"|<span style="color:navy>'''The value of RDT compared with microscopy: thick blood films'''</span> Assay quality: not all are the same WHO Heat stability of the RDT card: storage Age of card or reagent:storage Lot to lot variability in assay qua...") |
No edit summary |
||
| (25 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
{{DISPLAYTITLE:<span style="position: absolute; clip: rect(1px 1px 1px 1px); clip: rect(1px, 1px, 1px, 1px);">{{FULLPAGENAME}}</span>}} | |||
---- | ---- | ||
'''Navigation'''</br> | '''Navigation'''</br> | ||
[[Rapid diagnostic tests (RDTs)| | <span style="font-size:90%">[[MalariaETC Index|Main Malaria Index]]''</span></br> | ||
<span style="font-size:90%">>[[Rapid diagnostic tests (RDTs)|RDT main page]]''</span></br> | |||
<span style="font-size:90%">>>[[Interpretation guide: SINGLE BAND tests|Single Band Tests]]''</span></br> | |||
<span style="font-size:90%">>>>Current page: '''Practical reasons for test failure'''</span> | |||
---- | ---- | ||
{| class="wikitable" style="border-style: solid; border-width: 4px; color:black" | {| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; color:black" | ||
|colspan="1" style = "font-size:100%; color: | |colspan="1" style = "font-size:100%; color:blasck; background: FFFAFA"|<span style="color:navy>'''Practical considerations '''</span> | ||
<span style="font-size:90%">Bibilography: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652944/], [https://www.who.int/teams/global-malaria-programme/case-management/diagnosis/rapid-diagnostic-tests]</span> | |||
<span style="font-size:90%">'''1. Selection and procurement of MDTs'''</br> | |||
<span style="font-size:90%">(a) Quality of test design/production. There may be significant variation of performance between tests, users are advised to check test performance (see WHO testing information ref 2 above)</br>(b) Lot variability. Variability between different production batches has been observed and should be considered if RDT performance is less than expected.</br> | |||
Operator | <span style="font-size:90%">'''2. Stability and storage issues'''</br> | ||
<span style="font-size:90%">(a) RDTs typically have a shelf-life of 18–24 months providing storage is appropriateR.</br>(b) Tests can suffer degradation if stored in inappropriate heat or humidity: generally tests are stable in the range 2–30°C or higher, but these limits may be exceeded in many countries, and continuous product refrigeration to the point of use may not be guarenteed in developing countries. | |||
<span style="font-size:90%">'''3. Operator training'''</br> | |||
<span style="font-size:90%">(a)Problems in test usage may include inappropriate placement of test reagents or blood sample on RDT.</br>(b)Poor interpretion of faint lines.</br>(c) Inadequate training or reference materials | |||
Latest revision as of 16:05, 6 October 2024
Navigation
Main Malaria Index
>RDT main page
>>Single Band Tests
>>>Current page: Practical reasons for test failure
| Practical considerations
(a) Quality of test design/production. There may be significant variation of performance between tests, users are advised to check test performance (see WHO testing information ref 2 above) 2. Stability and storage issues (a) RDTs typically have a shelf-life of 18–24 months providing storage is appropriateR. 3. Operator training (a)Problems in test usage may include inappropriate placement of test reagents or blood sample on RDT. |