Prozone-like effect: Difference between revisions
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<span style="font-size:90%">[[MalariaETC Index|Main Malaria Index]]''</span></br> | <span style="font-size:90%">[[MalariaETC Index|Main Malaria Index]]''</span></br> | ||
<span style="font-size:90%">>[[Rapid diagnostic tests (RDTs)|RDT main page]]''</span></br> | <span style="font-size:90%">>[[Rapid diagnostic tests (RDTs)|RDT main page]]''</span></br> | ||
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Latest revision as of 09:41, 18 March 2025
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>>>Current page: The prozone-like effect
| The prozone-like (postzone) phenomenon
Most often the prozone effect is seen with HRP2 antigens. This effect means that where these is a very high parasitaemia (causing excess HRP2 antigen to be present) test can appear negative. It is thought that the presence of excess antigen means that the formation of appropriate antibody-antigen complexes is prevented so that the test does not function correctly. |