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<span style="font-size:140%; color:navy">'''Gallery of Schizonts'''</br></span>
<span style="font-size:140%; color:navy">'''Gallery of Schizonts'''</br></span>
</br>
</br>
<span style="font-size:90%">Schizont morphology is variable as they progress from late trophoxoites, dividing their chromatin into seprate distict masses (usually a schizont is defined by have more than two masses to distinguish them from rings with double dots). The morphological variability then continues as the merozoites separate before release. However, despite this, some features such as erythocyte size and shape, added dots, pigment distribution and the number of merozoites present can still be useful (as can the fact that they are rarely seen in ''P.falciparum''.</br></br>
<span style="font-size:90%">Schizont morphology is variable as they divide their chromatin into separate distinct separate masses (usually a schizont is defined by have more than two masses to distinguish them from rings that have double dots). This morphological variability then continues through successive divisions and maturation. Despite this however, some features such as erythocyte size and shape, added dots, pigment distribution and the number of merozoites present can still be useful (as can the fact that they are rarely seen in ''P.falciparum''.</br></br>
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<span style="font-size:90%">''' ''P.falciparum'' '''</span></br>
<span style="font-size:90%">''' ''P.falciparum'' '''</span></br>
<span style="font-size:90%">Loose and often "tatty" appearances with 8-16 merozoites and clumped pigment when mature. Rare in blood as they sequesterin tissues and circulating form may appear degenerate. Images show mature forms.</br>
<span style="font-size:90%">Loose and often "tatty" appearances with 16 or more merozoites and clumped pigment when mature. Rare in blood as they sequester in tissues and circulating form may appear degenerate. Images show mature forms.</br>
<gallery mode="nolines" heights=200px widths=200px>
<gallery mode="nolines" heights=200px widths=200px>
File:PFS1p.jpg|<span style="font-size:80%">Variable merozoite number, clumped pigment</span>|link={{filepath:PFS1p.jpg}}
File:PFS1p.jpg|<span style="font-size:80%">Variable merozoite number, clumped pigment</span>|link={{filepath:PFS1p.jpg}}
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File:PVS1.jpg|<span style="font-size:80%">Similar to previous, note Schüffner's dots</span>|link={{filepath:PVS1.jpg}}
File:PVS1.jpg|<span style="font-size:80%">Similar to previous, note Schüffner's dots</span>|link={{filepath:PVS1.jpg}}
File:PVS2.jpg|<span style="font-size:80%">Maturing form with separate merozoites</span>|link={{filepath:PVS2.jpg}}
File:PVS2.jpg|<span style="font-size:80%">Maturing form with separate merozoites</span>|link={{filepath:PVS2.jpg}}
File:PVS3.jpg|<span style="font-size:80%">Large mature form</span>|link={{filepath:PVS3.jpg}}
File:PVS3.jpg|<span style="font-size:80%">Large mature form, note patchy pigment</span>|link={{filepath:PVS3.jpg}}
</gallery>"
</gallery>"
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<span style="font-size:90%">''' ''P.ovale'' '''</span></br>
<span style="font-size:90%">''' ''P.ovale'' '''</span></br>
<span style="font-size:90%">Share many features with ''P.vivax'' and may not be easy to distinguish, tend not to be as large with up to 16 merozoites. Ovoid shape and fimbriation of red cells may be present together with James' dots. Pigment has a patchy distribution.
<span style="font-size:90%">Share many features with ''P.vivax'' and may not be easy to distinguish, tend not to be as large with fewer merozoites (up to 16). Ovoid shape and fimbriation of red cells may be present together with James' dots. Pigment has a patchy distribution.
<gallery mode="nolines" heights=200px widths=200px>
<gallery mode="nolines" heights=200px widths=200px>
File:POS1.jpg|<span style="font-size:80%">Ring form retained, fimbriationa and dots</span>|link={{filepath:POS1.jpg}}
File:POS1.jpg|<span style="font-size:80%">Early small form note James' dots</span>|link={{filepath:POS1.jpg}}
File:POS3.jpg|<span style="font-size:80%">Ring form retained, ovoid red cell</span>|link={{filepath:POS3.jpg}}
File:POS3.jpg|<span style="font-size:80%">Early form, merozoites still form a single mass</span>|link={{filepath:POS3.jpg}}
File:POS2.jpg|<span style="font-size:80%">Solid parasite, red cell fimbriation ("comet form")</span>|link={{filepath:POS2.jpg}}
File:POS2.jpg|<span style="font-size:80%">Small mature form with separated merozoites</span>|link={{filepath:POS2.jpg}}
File:POS4.jpg|<span style="font-size:80%">Solid parasite, red cell fimbriation</span>|link={{filepath:POS4.jpg}}</gallery>"
File:POS4.jpg|<span style="font-size:80%">Mature larger form, note ovoid shape</span>|link={{filepath:POS4.jpg}}</gallery>"
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<span style="font-size:90%">''' ''P.malariae'' '''</span></br>
<span style="font-size:90%">''' ''P.malariae'' '''</span></br>
<span style="font-size:90%">Small and often neat parasites with few merozoites when mature (generally around 8). Often there is a central clump of pigment with merozoites arranged around this (daisy head appearance).
<span style="font-size:90%">Small and often neat parasites with few merozoites when mature (generally around 8-12). Often there is a central clump of pigment with merozoites arranged around this (daisy head appearance).
<gallery mode="nolines" heights=200px widths=200px>
<gallery mode="nolines" heights=200px widths=200px>
File:PMS1.jpg|<span style="font-size:80%">Early elongated form, small red cell</span>|link={{filepath:PMS1.jpg}}
File:PMS1.jpg|<span style="font-size:80%">Early schizont with multiple chromatin dots</span>|link={{filepath:PMS1.jpg}}
File:PMS2.jpg|<span style="font-size:80%">A full band across the red cells</span>|link={{filepath:PMS2.jpg}}
File:PMS2.jpg|<span style="font-size:80%">A daisy with merozoites around central pigment</span>|link={{filepath:PMS2.jpg}}
File:PMS3.jpg|<span style="font-size:80%">An open angular parasite, note pigment</span>|link={{filepath:PMS3g.jpg}}
File:PMS3.jpg|<span style="font-size:80%">A less well formed daisy, note small size</span>|link={{filepath:PMS3.jpg}}
File:PMS4.jpg|<span style="font-size:80%">Angularity form</span>|link={{filepath:PMS4.jpg}}
File:PMS4.jpg|<span style="font-size:80%">Late form prior to merozoite release</span>|link={{filepath:PMS4.jpg}}
</gallery>"
</gallery>"
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<span style="font-size:90%">Similar in appearance to ''P.malariae''. The forms tend to be small with relatively few merozoites present. Pigment tend to form a clump.
<span style="font-size:90%">Similar in appearance to ''P.malariae''. The forms tend to be small with relatively few merozoites present. Pigment tend to form a clump.
<gallery mode="nolines" heights=200px widths=200px>
<gallery mode="nolines" heights=200px widths=200px>
File:PKS3.jpg|<span style="font-size:80%">Mixed irregular rings sparse dots</span>|link={{filepath:PKS3.jpg}}
File:PKS3.jpg|<span style="font-size:80%">Early form with few chromatin masses</span>|link={{filepath:PKS3.jpg}}
File:PKS2.jpg|<span style="font-size:80%">Elongated parasite forms</span>|link={{filepath:PKS2.jpg}}
File:PKS2.jpg|<span style="font-size:80%">Almost a daisy with central clumped pigment</span>|link={{filepath:PKS2.jpg}}
File:PKS1.jpg|<span style="font-size:80%">Solid and angular forms</span>|link={{filepath:PKS1.jpg}}
File:PKS1.jpg|<span style="font-size:80%">Prior to release of merozoites</span>|link={{filepath:PKS1.jpg}}
File:PKS4.jpg|<span style="font-size:80%">Mixed forms, dots and pigment</span>|link={{filepath:PKS4.jpg}}
File:PKS4.jpg|<span style="font-size:80%">Immediately before merozoite release</span>|link={{filepath:PKS4.jpg}}
</gallery>
</gallery>
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Latest revision as of 13:29, 17 March 2025

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Gallery of Schizonts
Schizont morphology is variable as they divide their chromatin into separate distinct separate masses (usually a schizont is defined by have more than two masses to distinguish them from rings that have double dots). This morphological variability then continues through successive divisions and maturation. Despite this however, some features such as erythocyte size and shape, added dots, pigment distribution and the number of merozoites present can still be useful (as can the fact that they are rarely seen in P.falciparum.

P.falciparum
Loose and often "tatty" appearances with 16 or more merozoites and clumped pigment when mature. Rare in blood as they sequester in tissues and circulating form may appear degenerate. Images show mature forms.

  • Variable merozoite number, clumped pigment

    Variable merozoite number, clumped pigment

  • Degenerate small merozoite

    Degenerate small merozoite

  • Large merozoites

    Large merozoites

  • Large merozoites

    Large merozoites

"

P.vivax
Charactertically large and Schüffner's dots may be seen. The merozoites tend to pack the red cell with numbers up to 16-32 in mature merozoites. Pigment has diffuse distribution. Images show a maturing sequence.

  • Early form with separate chromatin but no individual merozoites

    Early form with separate chromatin but no individual merozoites

  • Similar to previous, note Schüffner's dots

    Similar to previous, note Schüffner's dots

  • Maturing form with separate merozoites

    Maturing form with separate merozoites

  • Large mature form, note patchy pigment

    Large mature form, note patchy pigment

"

P.ovale
Share many features with P.vivax and may not be easy to distinguish, tend not to be as large with fewer merozoites (up to 16). Ovoid shape and fimbriation of red cells may be present together with James' dots. Pigment has a patchy distribution.

  • Early small form note James' dots

    Early small form note James' dots

  • Early form, merozoites still form a single mass

    Early form, merozoites still form a single mass

  • Small mature form with separated merozoites

    Small mature form with separated merozoites

  • Mature larger form, note ovoid shape

    Mature larger form, note ovoid shape

"

P.malariae
Small and often neat parasites with few merozoites when mature (generally around 8-12). Often there is a central clump of pigment with merozoites arranged around this (daisy head appearance).

  • Early schizont with multiple chromatin dots

    Early schizont with multiple chromatin dots

  • A daisy with merozoites around central pigment

    A daisy with merozoites around central pigment

  • A less well formed daisy, note small size

    A less well formed daisy, note small size

  • Late form prior to merozoite release

    Late form prior to merozoite release

"

P.knowlesi
Similar in appearance to P.malariae. The forms tend to be small with relatively few merozoites present. Pigment tend to form a clump.

  • Early form with few chromatin masses

    Early form with few chromatin masses

  • Almost a daisy with central clumped pigment

    Almost a daisy with central clumped pigment

  • Prior to release of merozoites

    Prior to release of merozoites

  • Immediately before merozoite release

    Immediately before merozoite release

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