RDT Quiz A Q1: Difference between revisions

Latest revision as of 00:10, 26 November 2024

RDT Quiz A Q1

RDT tests use specific antibodies to identify the malaria species. But are these tests equally effective for diagnosing all species?

Explanation of correct answer (click "Expand").

Short answer taken from section "Main RDT page" (see the section for full details and links).

The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests (the specific section in the main section provides more detail).

*P.falciparum*
At high parasitaemia expect high sensitivity (90-95%). This declines when parasite levels are lower (45-70%)
*P.vivax*
Expect moderate to high sensitivity at high parasitaemia (70-90%). This declines markedly when parasite levels are lower (30-60%)
*P.ovale & P.malarae*
Generally sensitivity is poor (approximately half the sensitivity shown for P.vivax)
*P.knowlesi*
Reports suggest variable sensitivity that may depend on test used, RDTs are reported tp detect this species well when parasitaemia is high.

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-<span style="font-size:90%">[[Rapid_diagnostic_tests_(RDTs)|back]]</span></br>
+<span style="font-size:90%">[[Rapid_diagnostic_tests_(RDTs)|Back to RDT Page]]</span></br></br>
+{| class="wikitable" style="width:100%; border-style: solid; border-width: 2px; border-color:teal"
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+|colspan="1" style = "font-size:130%; color:black; background: FFFAFA"|<span style="color:black>'''RDT Quiz A Q1'''</span>
-{| class="wikitable" style="width:90%; border-style: solid; border-width: 4px; border-color:teal"
+</br><span style="font-size:90%">RDT tests use specific antibodies to identify the malaria species. But are these tests equally effective for diagnosing all species?</br></br></span>
-|colspan="1" style = "font-size:130%; color:black; background: FFFAFA"|<span style="color:black>'''RDT Quiz A'''</span>
+<gallery mode="nolines" widths=100px heights=100px>
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+File:Mosquito.png|link={{filepath:Mosquito.png}}
+</gallery>
 <quiz display=simple>
-{1. For which 2 malarial species do appropriate RDT tests have best sensitivity ('''make two selections''')?
+{<span style="font-size:90%">When using an appropriate RDT tests which species are identified with good sensitivity (80-90%)? '''Make two selections'''</br></br>
 |type="[]"}
-+ ''P.falciparum''
++<span style="font-size:90%"> ''P.falciparum''
-+ ''P.vivax''
++<span style="font-size:90%"> ''P.vivax''
-- ''P.ovale''
+-<span style="font-size:90%"> ''P.ovale''
-- ''P.malariae''
+-<span style="font-size:90%"> ''P.malariae''
-- ''P.knowlesi''
+-<span style="font-size:90%"> ''P.knowlesi''
 </quiz>
 {| class="mw-collapsible mw-collapsed wikitable"
-! colspan="1" | Explanation of correct answer (click "Expand")
+! colspan="1" |<span style="font-size:90%">Explanation of correct answer (click "Expand").</span>
 |-
-|</b><span style="font-size:90%">The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests when suitable species-specific together with pan-malarial antibodies are used. The table is only a broad summary. </span></br></br>
+|</b> <span style="font-size:90%">''Short answer taken from section "Main RDT page" (see the section for full details and links)''.</br></br>The different malaria species are detected with different sensitivity. The table below provides an overall summary of the sensitivity that can be expected for RDT tests (the specific section in the main section provides more detail)''.</span></br></br>
 <div style="width:100%; font-size:90%;">
 {| class="wikitable" style="border-style: solid; border-width: 4px; color:black; font-size:90%;"
-!colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%">''' ''P.falciparum<sup>1</sup> '''</br>
+!colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%">''' ''P.falciparum'''</br>
 |-
-!colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">At high parasitaemia expect high sensitivity (90-95%). This declines when parasite levels are lower (45-70%)<sup>2</sup>
+!colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">At high parasitaemia expect high sensitivity (90-95%). This declines when parasite levels are lower (45-70%)
 |-
 !colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%;">''' ''P.vivax'' '''</span></br>
 |-
-!colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">Expect moderate to high sensitivity at high parasitaemia (70-90%). This declines markedly when parasite levels are lower (30-60%)<sup>2</sup>
+!colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">Expect moderate to high sensitivity at high parasitaemia (70-90%). This declines markedly when parasite levels are lower (30-60%)
 |-
 !colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%;">''' ''P.ovale & P.malarae'' '''</span></br>
@@ Line 36: / Line 37: @@
 !colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">Generally sensitivity is poor (approximately half the sensitivity shown for ''P.vivax'')
 |-
-!colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%;">''' ''P.knowlesi''<sup>3</sup> '''</span></br>
+!colspan="1" style = "background:#e1f1fd; border:solid; border-width: 3px;"|<span style="font-size:90%;">''' ''P.knowlesi'' '''</span></br>
 |-
 !colspan="1" style = "background:white; border:solid; border-width: 1px; color:black"|<span style="font-size:90%">Reports suggest variable sensitivity that may depend on test used, RDTs are reported tp detect this species well when parasitaemia is high.
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 |}
 </div>
-<span style="font-size:80%">Notes:</br></span>
-<span style="font-size:80%"><sup>1</sup> HRP2 mutation mean that in some geographical areas the diagnostic sensitivity may be significantly lower for HRP2-based tests (see below)</br></span>
-<span style="font-size:80%"><sup>2</sup> Low parasite number is considered as (<1000 parasites/μL) a level that may cause symptoms in children or non-immune travellers</br></span>
-<span style="font-size:80%"><sup>3</sup> There have been relatively few studies with this species so caution is required in RDT interpretation</br></span>
-</br>
 |}
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 |colspan="1" style = "font-size:90%; color:black|<span style="color:black>[[RDT_Quiz_A_Q2|Go to next question (2 of 5)]]</span>

RDT Quiz A Q1: Difference between revisions

From MalariaETC

Latest revision as of 00:10, 26 November 2024